منابع مشابه
Ion concentration dynamics as a mechanism for neuronal bursting.
We describe a simple conductance-based model neuron that includes intra- and extracellular ion concentration dynamics and show that this model exhibits periodic bursting. The bursting arises as the fast-spiking behavior of the neuron is modulated by the slow oscillatory behavior in the ion concentration variables and vice versa. By separating these time scales and studying the bifurcation struc...
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*Correspondence: [email protected] The College of New Jersey, Department of Physics, 08628 Ewing, NJ, USA Abstract Using single-cell laser scanning photostimulation (LSPS) combined with broad-field calcium imaging, we measured the functional connectivity of neuronal cultures before and after the developmental appearance of network bursting. From these data, network properties were determined for...
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Exploiting the specific structure of neuron conductance-based models, the paper investigates the mathematical modeling of neuronal bursting. The proposed approach combines singularity theory and geometric singular perturbations to unfold the geometry of multiple time-scales attractors in the neighborhood of high-codimension singularities. We detect a three-time scale bursting attractor in the u...
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ژورنال
عنوان ژورنال: Journal of Biological Physics
سال: 2011
ISSN: 0092-0606,1573-0689
DOI: 10.1007/s10867-011-9227-7